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Q: Sigma-minus method is used to determine
  • A. Excretion rate constant
  • B. Metabolic rate constant
  • C. Elimination rate constant
  • D. Absorption rate constant
Correct Answer: Option C - Sigma-minus is used to determine the elimination rate constant and it is an alternative method for the calculation of elimination rate (Kel) from urinary excretion data.
C. Sigma-minus is used to determine the elimination rate constant and it is an alternative method for the calculation of elimination rate (Kel) from urinary excretion data.

Explanations:

Sigma-minus is used to determine the elimination rate constant and it is an alternative method for the calculation of elimination rate (Kel) from urinary excretion data.