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Q: Isoniazid is a primary anti-tubercular agent that
  • A. Requires pyridoxine supplementation
  • B. Causes ocular complication that are reversible if the drug is discontinued
  • C. Is ototoxic and nephrotoxic
  • D. Should never be used due to its hepatotoxicity
Correct Answer: Option C - Ototoxicity and nephrotoxicity are clinically significant dose -related adverse effects associated with second-line anti-tubercular injectable drugs (aminoglycosides and capreomycin) used during intensive phase of treatment of multi -drug resistant tuberculosis patients. Isoniazid is in class of medications called anti tuberculosis agents. It works by killing the bacteria that cause tuberculosis.
C. Ototoxicity and nephrotoxicity are clinically significant dose -related adverse effects associated with second-line anti-tubercular injectable drugs (aminoglycosides and capreomycin) used during intensive phase of treatment of multi -drug resistant tuberculosis patients. Isoniazid is in class of medications called anti tuberculosis agents. It works by killing the bacteria that cause tuberculosis.

Explanations:

Ototoxicity and nephrotoxicity are clinically significant dose -related adverse effects associated with second-line anti-tubercular injectable drugs (aminoglycosides and capreomycin) used during intensive phase of treatment of multi -drug resistant tuberculosis patients. Isoniazid is in class of medications called anti tuberculosis agents. It works by killing the bacteria that cause tuberculosis.