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Q: A polyene antibiotic
  • A. Amphotericin B
  • B. Griseofulvin
  • C. Fusidic acid
  • D. Tobramycin
Correct Answer: Option A - A polyene antibiotic is Amphotericin B. The other examples of polyene antibiotics are Nystatin and pimaricin. The polyene antibiotics are the only group of antifungal antibiotics that directly target the plasma membrane via a specific interaction with the main fungal sterol ergosterol, often resulting in membrane permeabilization. The polyene antibiotics comprise a class of molecules that are toxic to fungi but not to bacteria. They are produced by the bacteria streptomycese.
A. A polyene antibiotic is Amphotericin B. The other examples of polyene antibiotics are Nystatin and pimaricin. The polyene antibiotics are the only group of antifungal antibiotics that directly target the plasma membrane via a specific interaction with the main fungal sterol ergosterol, often resulting in membrane permeabilization. The polyene antibiotics comprise a class of molecules that are toxic to fungi but not to bacteria. They are produced by the bacteria streptomycese.

Explanations:

A polyene antibiotic is Amphotericin B. The other examples of polyene antibiotics are Nystatin and pimaricin. The polyene antibiotics are the only group of antifungal antibiotics that directly target the plasma membrane via a specific interaction with the main fungal sterol ergosterol, often resulting in membrane permeabilization. The polyene antibiotics comprise a class of molecules that are toxic to fungi but not to bacteria. They are produced by the bacteria streptomycese.