Correct Answer:
Option D - The Anti-metabolites represent a relatively large group of anticancer agents that structurally resemble natural substrates, but differ enough to interfere with their metabolism included are folic acid antagonists, such as methotrexate, purine antimetabolites such as 6- mercaptopurine, 6- thioguanine, fludarabine phosphate, pentostatin and cladribine.
D. The Anti-metabolites represent a relatively large group of anticancer agents that structurally resemble natural substrates, but differ enough to interfere with their metabolism included are folic acid antagonists, such as methotrexate, purine antimetabolites such as 6- mercaptopurine, 6- thioguanine, fludarabine phosphate, pentostatin and cladribine.