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Q: Identify the centrally acting analgesic that has low affinity for μ, k, d receptors and inhibits the reuptake of NE and 5-HT.
  • A. Tramadol
  • B. Methadone
  • C. Butorphanol
  • D. Burenorphine
Correct Answer: Option A - Tramadol has low affinity for μ and K, D opioid receptors and inhibits the reuptake of both norepinephrine and serotonin (5 HT) neurotransmitters. It stimulates the dopamine receptors and also inhibits the gamma amino butyric acid release in central nervous system.
A. Tramadol has low affinity for μ and K, D opioid receptors and inhibits the reuptake of both norepinephrine and serotonin (5 HT) neurotransmitters. It stimulates the dopamine receptors and also inhibits the gamma amino butyric acid release in central nervous system.

Explanations:

Tramadol has low affinity for μ and K, D opioid receptors and inhibits the reuptake of both norepinephrine and serotonin (5 HT) neurotransmitters. It stimulates the dopamine receptors and also inhibits the gamma amino butyric acid release in central nervous system.